tag:blogger.com,1999:blog-3215661876653517169.post7808012715165303324..comments2023-12-21T01:22:02.387-05:00Comments on Genome Toolbox: Estimate Combined Percent Familial Risk Explained by GWAS LociUnknownnoreply@blogger.comBlogger1125tag:blogger.com,1999:blog-3215661876653517169.post-1016126676530319902017-10-29T11:50:41.824-04:002017-10-29T11:50:41.824-04:00I am having difficulty deriving the original formu...I am having difficulty deriving the original formula used by Cox et al. or your arithmetically equivalent version given here lambda due to allele k to overall familial risk. Iam wondering how one might explain how to derive this formula from a simple pedigree assuming one affected individual and a first degree relativeNussbaumhttps://www.blogger.com/profile/16413410587680627684noreply@blogger.com